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Venom Honey Bee (Apis mellifera) IgG4

Test Code: 90122

Cpt Code:

86001 (x1)

Clinical Utility

Venom-specific IgG & IgG4 have been reported to be helpful in evaluating and optimizing therapy in patients with venom hypersensitivity. Low levels of so called “IgG blocking antibody” are associated with the more serious reactions to challenge.

Procedure

Enzyme immunoassay (FEIA). A standard curve is used to calculate the specific IgG concentrations. The calibrators are referenced to the International Reference Preparation for serum immunoglobulins. This test has not been cleared or approved for diagnostic use by the U.S. Food and Drug Administration.

Assay Range

 

  mcg/mL of IgG4
Lower Limit of Quantitation 0.15
Upper Limit of Quantitation 30.0

Reference ranges vary by allergen.

Turnaround Time

Setup: M-W-F. TAT: 2-3 business days from receipt of specimen.

Specimen Information

Serum -0.5 mL. Collect 1-2 mL whole blood in red top tube, centrifuge and transfer 0.5 mL serum into a transfer tube (Minimum Volume). Ship at ambient or frozen temperature Monday through Friday. Specimens are stable for 1 week ambient, 4 weeks refrigerated; freeze for storage greater than 4 weeks.

Disclaimer

Specimens are approved for testing in New York only when indicated in the Specimen Information field above.

The CPT codes provided are based on Viracor-IBT's interpretation of the American Medical Association's Current Procedural Terminology (CPT) codes and are provided for general informational purposes only. CPT coding is the sole responsibility of the billing party. Questions regarding coding should be addressed to your local Medicare carrier. Viracor-IBT assumes no responsibility for billing errors due to reliance on the CPT codes illustrated in this material.

References

Hamilton RG. Assessment of human allergic disease. In: Rich RR, Fleisher TA, Shearer WT, Kotzin BL and Schroeder HW (eds). Clinical Immunology, Principles & Practice, 2nd Ed., Chapter 124, Mosby, New York.

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